Description

1-Deazaadenosine is a chemically modified nucleoside analog, where a nitrogen atom in the adenine base is replaced by a carbon atom. This structural modification makes it a valuable biochemical tool and a key intermediate in the research and development of novel therapeutic agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for applications in medicinal chemistry, enzymology, and as a building block for more complex nucleoside derivatives.

Application

• Medicinal Chemistry Research: Serves as a crucial scaffold for the synthesis of novel nucleoside-based drug candidates targeting viral infections and cancer.
• Biochemical Tool: Used in enzymatic studies to investigate substrate specificity and the mechanism of action of adenosine-metabolizing enzymes.
• Antiviral/Anticancer Agent Development: Acts as a precursor in the synthesis of potential antiviral and antitumor prodrugs.
• Nucleoside Analog Synthesis: A fundamental building block for creating a library of modified nucleosides with altered biological activity.
• Academic & Institutional Research: Employed in university and research institute labs for fundamental studies in chemical biology and nucleic acid chemistry.

Basic Information

Product Name	1-Deazaadenosine
CAS No.	14432-09-8
Molecular Formula	C11H14N4O4
Molecular Weight	266.26 g/mol
Synonyms	1-Deazaadenosine; 9-β-D-Ribofuranosyl-1-deazaadenine; 1-Deaza-adenosine; 1-Carbaadenosine; 1,7-Dideazaadenosine (less common); 1-Deaza-A; Adenosine, 1-deaza-; 1-Deaza-9-β-D-ribofuranosyladenine
EINECS	Contact for details

Quality Control

Our 1-Deazaadenosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.