Description

8-[Acetyl(9H-Fluoren-2-Yl)Amino]Guanosine is a chemically modified nucleoside derivative, specifically a guanosine analog, designed for advanced research and development applications. This compound is of significant interest in the fields of medicinal chemistry and biochemistry for its potential role in studying nucleic acid interactions and as a building block for novel oligonucleotide synthesis. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing targeted therapies and diagnostic tools.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or precursor in the synthesis of novel nucleoside-based therapeutics, including potential antiviral or anticancer agents.
• Biochemical Probes: Used in the development of fluorescent or affinity-labeled probes for studying enzyme mechanisms, such as polymerases and helicases, and nucleic acid-protein interactions.
• Oligonucleotide Synthesis: Acts as a modified building block for the solid-phase synthesis of specialized oligonucleotides with tailored properties for antisense or siRNA applications.
• Academic Research: Employed in university and institutional labs for fundamental studies on DNA/RNA structure, function, and the biochemical pathways involving modified nucleosides.
• Diagnostic Development: Potential use in creating components for diagnostic assays that detect specific genetic markers or enzymatic activities.

Basic Information

Product Name	8-[Acetyl(9H-Fluoren-2-Yl)Amino]Guanosine
CAS No.	14395-34-7
Molecular Formula	C25H22N6O5
Molecular Weight	486.48 g/mol
Synonyms	8-[Acetyl(9H-fluoren-2-yl)amino]guanosine; 8-(N-Acetyl-N-2-fluorenyl)aminoguanosine; Guanosine, 8-[acetyl(9H-fluoren-2-yl)amino]-; 8-(Acetylamino)-N-(9H-fluoren-2-yl)guanosine; 8-Fluorenylacetylamino guanosine; Modified Guanosine Derivative; Fmoc-protected guanosine analog (common description)
EINECS	Contact for details

Quality Control

Our 8-[Acetyl(9H-Fluoren-2-Yl)Amino]Guanosine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen in a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.