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2-(6-Aminopurin-3-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol CAS NO 14365-78-7


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CAS No.:14365-78-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(6-Aminopurin-3-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol is a high-purity nucleoside derivative, also known as 3'-Deoxyadenosine. This compound is a critical building block in organic synthesis and biochemical research, valued for its role in modifying nucleic acid structures. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of fine chemicals and diagnostic reagents for developing novel therapeutics and probes.

Application

  • Pharmaceutical Intermediate: Serves as a key synthon in the research and development of nucleoside-based antiviral and anticancer agents.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for investigating nucleic acid metabolism and function.
  • Probe Synthesis: Acts as a precursor for labeled nucleotides used in diagnostic assays, sequencing, and molecular biology techniques.
  • Fine Chemical Synthesis: Employed in the custom synthesis of modified oligonucleotides and other specialized organic molecules.
  • Academic & Industrial R&D: Essential for fundamental research in medicinal chemistry, chemical biology, and related life science fields.

Basic Information

Product Name 2-(6-Aminopurin-3-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol
CAS No. 14365-78-7
Molecular Formula C11H15N5O4
Molecular Weight 281.27 g/mol
Synonyms 3'-Deoxyadenosine; Cordycepin Impurity; 9-(3-Deoxy-β-D-ribofuranosyl)adenine; 3'-Deoxy-D-adenosine; Cordycepin Related Compound A; 3'-dA; Adenosine, 3'-deoxy-; 3'-Deoxyadenosine (Cordycepin)
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Quality Control

Our 2-(6-Aminopurin-3-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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