Description

2'-Deoxy-B-L-Adenosine is a stereoisomer of the fundamental nucleoside 2'-deoxyadenosine, distinguished by its β-L-configuration. This specific stereochemistry makes it a valuable building block and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of nucleoside chemistry, antiviral drug discovery, and molecular biology. The compound is essential for studying enzyme-substrate interactions, synthesizing modified oligonucleotides, and exploring novel therapeutic agents.

Application

• Biochemical Research: Critical intermediate in the study of nucleoside metabolism, enzyme kinetics, and stereospecific biochemical pathways.
• Pharmaceutical R&D: Serves as a key precursor or analog in the synthesis of potential antiviral and anticancer nucleoside prodrugs.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in analytical laboratories.
• Oligonucleotide Synthesis: Building block for the chemical synthesis of specialized oligonucleotides with specific stereochemical properties for diagnostic or therapeutic applications.
• Enzymology Studies: Substrate for investigating the activity and specificity of nucleoside kinases, polymerases, and other nucleic acid-modifying enzymes.

Basic Information

Product Name	2'-Deoxy-B-L-Adenosine
CAS No.	14365-45-8
Molecular Formula	C10H13N5O3
Molecular Weight	251.24 g/mol
Synonyms	2'-Deoxy-β-L-adenosine; β-L-2'-Deoxyadenosine; L-2'-Deoxyadenosine; 9-[(2R,3S,5R)-3-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurine; Adenine β-L-2'-deoxyriboside; 2'-Deoxyadenosine, β-L-form; 2'-dA (β-L)
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-B-L-Adenosine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our commitment is to deliver material of the highest consistency and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.