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5'-Aminoadenosine CAS NO 14365-44-7


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CAS No.:14365-44-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5'-Aminoadenosine is a modified nucleoside derivative where an amino group is introduced at the 5' position of the ribose sugar. This functionalization makes it a valuable building block and intermediate in the synthesis of more complex nucleotide analogs and pharmaceutical agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug discovery, biochemical research, and the development of novel therapeutics.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of adenosine receptor agonists/antagonists and other nucleoside-based drugs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases and other nucleotide-processing enzymes.
  • Probe and Diagnostic Development: Serves as a starting material for creating labeled nucleotides or probes for molecular biology and diagnostic assays.
  • Antiviral/Anticancer Agent Research: Investigated as a core structure for developing novel therapeutic compounds targeting viral replication or cellular proliferation.
  • Cross-linking Agent Synthesis: Utilized in the preparation of nucleotide-based cross-linkers for studying nucleic acid-protein interactions.
  • Material Science: Potential use in creating functionalized surfaces or polymers for biosensor applications.

Basic Information

Product Name 5'-Aminoadenosine
CAS No. 14365-44-7
Molecular Formula C10H14N6O4
Molecular Weight 282.26 g/mol
Synonyms 5'-Amino-5'-deoxyadenosine; Adenosine, 5'-amino-5'-deoxy-; 5'-Deoxy-5'-aminoadenosine; 9-β-D-Ribofuranosyladenine, 5'-amino-5'-deoxy-; 5'-ADA; 5'-Amino-5'-deoxy-9-β-D-ribofuranosyladenine
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Quality Control

Our 5'-Aminoadenosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/IR) Conforms
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 10 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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