Description

Guanosine 5'-(Tetrasodium Triphosphate) is a high-purity nucleotide derivative essential for biochemical research and pharmaceutical development. This compound serves as a critical building block and energy source in enzymatic reactions, particularly those involving RNA synthesis and cellular metabolism. It is primarily utilized by research institutions, diagnostic manufacturers, and companies developing therapeutic nucleotides and molecular biology kits.

Application

• Biochemical Research: As a substrate for RNA polymerases, kinases, and other nucleotide-dependent enzymes in in vitro studies.
• Diagnostic Reagent Manufacturing: A key component in the formulation of kits for molecular diagnostics, including PCR and sequencing applications.
• Pharmaceutical Intermediates: Used in the synthesis of novel nucleotide-based therapeutics, such as antiviral and anticancer prodrugs.
• Enzymology Studies: Employed to study enzyme kinetics, mechanisms, and inhibition profiles of GTP-utilizing proteins.
• Cell Culture & Metabolism: Supplemented in specialized media to support cellular energy metabolism and nucleotide synthesis pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and diagnostic production.

Basic Information

Product Name	Guanosine 5'-(Tetrasodium Triphosphate)
CAS No.	14356-96-8
Molecular Formula	C10H12N5Na4O14P3
Molecular Weight	629.13 g/mol (anhydrous basis)
Synonyms	Guanosine-5'-triphosphate tetrasodium salt; GTP tetrasodium salt; 5'-GTP Na4; Guanosine 5'-triphosphoric acid tetrasodium salt; Sodium Guanosine Triphosphate; Guanosine triphosphate tetrasodium salt hydrate; GtpNa4
EINECS	Contact for details

Quality Control

Our Guanosine 5'-(Tetrasodium Triphosphate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening, to ensure it meets the stringent requirements for research and diagnostic use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Purity (HPLC)	≥ 98% (Total nucleotide content)
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.