Description

2,2-Bis-(Trifluoromethyl) Butyryl Fluoride is a highly fluorinated, reactive acyl fluoride building block. This compound is valued for its ability to introduce the robust and lipophilic bis(trifluoromethyl) group into complex molecules, significantly altering their physical and chemical properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) with enhanced metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorinated moiety improves efficacy and environmental profile.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier for creating specialty polymers with exceptional chemical resistance, thermal stability, and low surface energy.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated components for display technologies and electronic materials.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the -COF group and CF3-rich side chains in complex organic transformations.
• Surface Modification Agent: Used to create hydrophobic and oleophobic coatings on various substrates.

Basic Information

Item	Details
Product Name	2,2-Bis-(Trifluoromethyl) Butyryl Fluoride
CAS No.	14316-81-5
Molecular Formula	C7H5F7O
Molecular Weight	238.10 g/mol
Synonyms	2,2-Bis(trifluoromethyl)butanoyl Fluoride; 2,2-Bis(trifluoromethyl)butyryl Fluoride; Butanoyl fluoride, 2,2-bis(trifluoromethyl)-; 2,2-Bis(trifluoromethyl)butyroyl Fluoride; Perfluoro-tert-butylacetyl Fluoride; 1,1,1,3,3,3-Hexafluoro-2-(trifluoromethyl)-2-propylcarbonyl Fluoride
EINECS	Contact for details

Quality Control

Our 2,2-Bis-(Trifluoromethyl) Butyryl Fluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, alcohols, and moisture. Due to its nature as a strong acid/organic solvent and highly volatile compound, appropriate secondary containment and handling procedures are recommended. Recommended storage temperature: 2-8°C (under inert atmosphere if specified).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.