Description

D-(-)-Prilocaine is the pure enantiomeric form of the widely used local anesthetic agent, Prilocaine. This high-purity chiral building block is critical for pharmaceutical research and development, particularly in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily utilized by advanced pharmaceutical manufacturers and research institutions focused on developing novel anesthetic formulations with improved safety and efficacy profiles.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure local anesthetic APIs.
• Analytical Reference Standard: Used as a high-purity standard in HPLC, GC, and other chromatographic methods for quality control and method development.
• Biochemical Research: Employed in studies investigating the stereospecificity of anesthetic action, receptor binding, and metabolic pathways.
• Formulation Development: Serves as a critical raw material in the R&D of new topical and injectable anesthetic preparations.
• Process Chemistry: Used in asymmetric synthesis and chiral resolution processes to produce single-isomer pharmaceutical compounds.

Basic Information

Product Name	D-(-)-Prilocaine
CAS No.	14289-32-8
Molecular Formula	C13H20N2O
Molecular Weight	220.31 g/mol
Synonyms	(R)-(-)-Prilocaine; (R)-2-(Propylamino)-o-propionotoluidide; D-(-)-N-(2-Methylphenyl)-2-(propylamino)propanamide; (-)-Prilocaine; (R)-Prilocaine; LAC-43 (enantiomer); Propitocaine (enantiomer); Citanest (enantiomer)
EINECS	Contact for details

Quality Control

Our D-(-)-Prilocaine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this hygroscopic (moisture-sensitive) compound.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.