Description

L-(+)-Prilocaine is a high-purity local anesthetic agent belonging to the amino amide class. It is valued for its rapid onset of action and favorable safety profile, particularly its lower potential for causing methemoglobinemia compared to other anesthetics in its class. This compound is essential for manufacturers in the pharmaceutical industry, specifically for the formulation of injectable anesthetic solutions and topical preparations used in medical and dental procedures.

Application

• Active Pharmaceutical Ingredient (API) in injectable local anesthetic formulations.
• Key component in topical anesthetic creams, gels, and ointments for dermal procedures.
• Used in dental anesthetic solutions for nerve block and infiltration anesthesia.
• Critical raw material in the research and development of new anesthetic drug combinations.
• Intermediate in the synthesis of more complex pharmaceutical compounds.
• Reference standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	L-(+)-Prilocaine
CAS No.	14289-31-7
Molecular Formula	C13H20N2O
Molecular Weight	220.31 g/mol
Synonyms	Prilocaine; (S)-(-)-2-(Propylamino)-o-propionotoluidide; L-Propivacaine; Citanest; Xylonest; Propitocaine; (±)-Prilocaine (racemic mixture); N-(2-Methylphenyl)-2-(propylamino)propanamide
EINECS	Contact for details

Quality Control

Our L-(+)-Prilocaine is produced under strict quality management systems. It undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) are provided with each batch, detailing parameters such as assay, enantiomeric purity, and impurity profiles. We can supply material compliant with relevant pharmacopeial monographs (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Enantiomeric Purity	≥ 99.0% (L-Form)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.