Description

3'-Deoxy-3'-Iodothymidine is a halogenated nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial intermediate in the synthesis of novel antiviral agents and as a molecular probe in biochemical studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleoside-based therapeutics and diagnostic tools.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving thymidine kinase and DNA polymerases.
• Antiviral Agent Development: Serves as a precursor for compounds being investigated for activity against various viral targets.
• Radiopharmaceutical Precursor: Potential use in the development of iodine-123 or iodine-131 labeled compounds for diagnostic imaging or therapy.
• Organic Synthesis: Valuable intermediate for introducing iodine and nucleoside motifs into more complex molecular architectures.

Basic Information

Product Name	3'-Deoxy-3'-Iodothymidine
CAS No.	14260-82-3
Molecular Formula	C10H13IN2O5
Molecular Weight	368.13 g/mol
Synonyms	3'-Iodo-3'-deoxythymidine; 3'-Deoxy-3'-iodothymidine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)-4-iodotetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione; 3'-Iodo-2',3'-dideoxythymidine; 3'-IDT; 3'-Iodothymidine; 3'-Iodo-2',3'-dideoxy-D-thymidine
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Iodothymidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.