Description

5'-Deoxy-5'-Iodouridine is a halogenated nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a versatile building block and a key intermediate in the synthesis of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism and DNA/RNA synthesis.
• Medicinal Chemistry: Serves as a key building block for structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Radiopharmaceuticals: Potential precursor for the development of iodine-labeled compounds for diagnostic imaging.
• Antisense Oligonucleotide Development: Can be incorporated into oligonucleotides to modify their stability and binding properties.

Basic Information

Item	Details
Product Name	5'-Deoxy-5'-Iodouridine
CAS No.	14259-58-6
Molecular Formula	C9H11IN2O5
Molecular Weight	354.10 g/mol
Synonyms	5'-Iodo-5'-deoxyuridine; 1-((2R,3S,5R)-5-Iodo-3-hydroxyoxolan-2-yl)pyrimidine-2,4-dione; 5'-Deoxy-5-iodouridine; 5-Iodo-5'-deoxyuridine; Uridine, 5'-deoxy-5-iodo-; 5'-Iododeoxyuridine
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5'-Iodouridine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.