Description

2,3,4,6-Tetra-o-Acetyl-α-D-Galactopyranosyl Chloride is a key glycosyl donor and protected sugar intermediate in synthetic carbohydrate chemistry. This compound matters for its critical role in the stereoselective construction of complex oligosaccharides and glycoconjugates, enabling precise chemical glycosylation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors developing novel therapeutics, vaccines, and biological probes.

Application

• Glycosylation Reagent: A crucial building block for the synthesis of complex oligosaccharides, glycoproteins, and glycolipids.
• Pharmaceutical Intermediate: Used in the research and production of carbohydrate-based drugs, including antiviral agents, antibiotics, and anticancer therapeutics.
• Glycoconjugate Synthesis: Essential for creating labeled sugars, glycoarrays, and neoglycoconjugates for biological studies and diagnostic assays.
• Carbohydrate Chemistry Research: A fundamental tool in academic and industrial R&D for exploring glycosylation mechanisms and developing new synthetic methodologies.
• Biochemical Probe Development: Serves as a precursor for synthesizing activity-based probes to study glycosidases and glycosyltransferases.
• Vaccine Adjuvant Development: Investigated for use in the synthesis of carbohydrate antigens and immunostimulatory compounds.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Galactopyranosyl Chloride
CAS No.	14227-87-3
Molecular Formula	C14H19ClO9
Molecular Weight	366.75 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl chloride; α-D-Galactopyranosyl chloride, 2,3,4,6-tetraacetate; Tetra-O-acetyl-α-D-galactopyranosyl chloride; Ac4α-D-Galp-Cl; 1-Chloro-2,3,4,6-tetra-O-acetyl-α-D-galactopyranose; α-D-Galactosyl chloride tetraacetate; (2R,3R,4S,5R,6R)-2-(Acetyloxymethyl)-6-chloro-3,4,5-tris(acetyloxy)tetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Galactopyranosyl Chloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]D20	+150° to +160° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.