Description

2-Chloro-3-isothiocyanato-prop-1-ene is a specialized organic building block containing both a reactive chloro and an isothiocyanate functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing heterocyclic compounds and functionalized polymers. It is primarily sought by research and development chemists in the agrochemical and pharmaceutical sectors for creating novel active ingredients and advanced materials. The compound's reactivity profile enables the construction of complex molecular architectures.

Application

• Agrochemical Intermediate: Key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the isothiocyanate moiety for biological activity.
• Pharmaceutical Research: Used in medicinal chemistry for the development of potential drug candidates, particularly those targeting specific enzymes or receptors.
• Polymer Modification: Serves as a cross-linking agent or functional monomer to introduce thiourea or thiazolidine linkages into polymer backbones, enhancing material properties.
• Chemical Synthesis: A versatile building block for constructing sulfur- and nitrogen-containing heterocycles, such as thiazoles and thiadiazoles, which are common scaffolds in fine chemicals.
• Bioconjugation Chemistry: The isothiocyanate group can react with amine groups under mild conditions, making it useful for labeling proteins or other biomolecules in research applications.

Basic Information

Product Name	2-Chloro-3-isothiocyanato-prop-1-ene
CAS No.	14214-31-4
Molecular Formula	C4H4ClNS
Molecular Weight	133.60 g/mol
Synonyms	1-Chloro-2-isothiocyanatoethene; 2-Chloroethenyl isothiocyanate; 2-Chlorovinyl isothiocyanate; 1-Chloro-2-isothiocyanatoethylene; (2-Chloroethenyl)isothiocyanate; 2-Chloro-1-isothiocyanatoethene; Vinyl chloride isothiocyanate; Allyl chloride isothiocyanate (related structure)
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-3-isothiocyanato-prop-1-ene adheres to stringent internal quality protocols. Every batch is analyzed using modern analytical techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee it meets your specific research or process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept tightly sealed when not in use and away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.