Description

2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl Isothiocyanate is a key glycosyl donor intermediate, specifically designed for the synthesis of thioglycosides. This compound is critical for researchers and manufacturers requiring high-purity building blocks for complex carbohydrate and glycoconjugate synthesis. It is primarily utilized in pharmaceutical R&D, agrochemical development, and advanced material science where precise glycosylation is essential.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel glycosidase inhibitors, anticancer agents, and other bioactive thioglycosides.
• Glycoconjugate Synthesis: Used for the chemical and enzymatic preparation of complex oligosaccharides, glycopeptides, and glycolipids for biological studies.
• Agrochemical Research: Acts as a building block for developing new glycosylated pesticides or plant growth regulators with modified activity and stability.
• Chemical Biology Probes: Employed in the creation of affinity labels, activity-based probes, and other tools for studying carbohydrate-processing enzymes.
• Material Science: Potential use in the surface functionalization of materials to introduce specific carbohydrate motifs for biosensing or biocompatibility applications.
• Standards and References: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl Isothiocyanate
CAS No.	14152-97-7
Molecular Formula	C15H19NO9S
Molecular Weight	389.38 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate; 1-Isothiocyanato-2,3,4,6-tetra-O-acetyl-β-D-glucopyranose; Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate; β-D-Glucopyranosyl isothiocyanate, 2,3,4,6-tetraacetate; Glucosyl isothiocyanate tetraacetate; Ac4GlcNCS
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Specific Rotation [α]20/D	-15° to -18° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.