Description

Ethoxyacetyl Chloride is a versatile and highly reactive acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the ethoxyacetyl functional group, enabling the production of complex molecules with tailored properties. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create active ingredients and sophisticated intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing ester and amide bonds in drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators by incorporating the ethoxyacetyl moiety.
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with specific functional groups.
• Peptide & Protein Research: Employed as an acylating agent for modifying amino acids or protecting groups in peptide synthesis.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of complex organic dyes and colorants.
• Liquid Crystal & OLED Materials: Building block for synthesizing advanced organic electronic materials.
• Cross-coupling Reactions: Serves as a substrate in various metal-catalyzed coupling reactions to form carbon-carbon bonds.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies.

Basic Information

Item	Detail
Product Name	Ethoxyacetyl Chloride
CAS No.	14077-58-8
Molecular Formula	C4H7ClO2
Molecular Weight	122.55 g/mol
Synonyms	2-Ethoxyacetyl chloride; Ethoxyacetic acid chloride; α-Ethoxyacetyl chloride; Chloro(ethoxy)acetaldehyde; Ethoxyacetic acid, chloride; 2-Ethoxyethanoyl chloride; Ethoxyacetylchloride; NSC 403124
EINECS	Contact for details

Quality Control

Our Ethoxyacetyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity, IR for identification, and titration for assay determination, to ensure it meets precise specifications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all quality parameters. We adhere to cGMP principles where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat and ignition sources. Due to its hygroscopic and highly volatile nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizers, and alcohols.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.15 g/cm³
Boiling Point	~145-150 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.