Description

Phosphoribosylamine is a key biochemical intermediate in the purine nucleotide biosynthesis pathway. Its role as a precursor in the synthesis of inosine monophosphate (IMP) makes it a compound of significant interest for research and development in biochemistry and life sciences. This high-purity material is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors, particularly those focused on nucleotide metabolism, enzyme studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Critical substrate for studying the enzymatic mechanisms of purine biosynthesis, particularly for phosphoribosylamine-glycine ligase (PurD).
• Pharmaceutical Development: Serves as a key building block in the research and synthesis of nucleotide analogs with potential antiviral or anticancer activity.
• Enzyme Assay Kits: Used as a standardized component in diagnostic and research kits designed to measure enzyme activity in the purine synthesis pathway.
• Metabolic Pathway Analysis: Employed in in vitro and cell culture studies to investigate nucleotide metabolism and its regulation.
• Academic & Industrial R&D: A fundamental reagent for universities and contract research organizations (CROs) exploring new targets in metabolic diseases.

Basic Information

Product Name	Phosphoribosylamine
CAS No.	14050-66-9
Molecular Formula	C5H12NO7P
Molecular Weight	229.12 g/mol
Synonyms	5-Phospho-D-ribosylamine; 5-O-Phosphono-D-ribofuranosylamine; PRA; D-Ribofuranosylamine 5-phosphate; 5-Phosphoribosylamine; 1-Amino-1-deoxy-D-ribose 5-phosphate; (2R,3R,4R,5R)-5-(Aminomethyl)tetrahydrofuran-2,3,4-triyl trihydrogen phosphate
EINECS	Contact for details

Quality Control

Our Phosphoribosylamine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.