Description

(R)-(+)-9-(2-Hydroxypropyl)Adenine is a chiral, nucleoside-derived compound of significant interest in advanced pharmaceutical research and development. This high-purity intermediate is valued for its role in the synthesis of novel antiviral agents and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleotide analogs and targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleic acid processing.
• Proteomics & Molecular Biology: Employed in the development of probes and tools for studying adenosine receptor interactions and signaling pathways.
• Process Chemistry: Serves as a critical starting material for the scalable production of active pharmaceutical ingredients (APIs) under GMP conditions.

Basic Information

Product Name	(R)-(+)-9-(2-Hydroxypropyl)Adenine
CAS No.	14047-28-0
Molecular Formula	C9H13N5O
Molecular Weight	207.23 g/mol
Synonyms	(R)-9-(2-Hydroxypropyl)adenine; (R)-(+)-HPMPA; (R)-HPMPA; (R)-9-(2-Hydroxy-1-methylethyl)adenine; (R)-N9-(2-Hydroxypropyl)adenine; (R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol; Adenine, 9-[(1R)-2-hydroxy-1-methylethyl]-
EINECS	Contact for details

Quality Control

Our (R)-(+)-9-(2-Hydroxypropyl)Adenine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and chiral analysis. We adhere to relevant industry standards for research-grade and pharmaceutical intermediate materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.