Description

1-(2,3-Epoxy-B-D-Lyxofuranosyl)Uracil is a specialized nucleoside analogue with a reactive epoxy functional group on its sugar moiety. This unique structure makes it a valuable intermediate for the synthesis of modified nucleic acids and potential antiviral or anticancer agents. It is primarily utilized by pharmaceutical research organizations, biotechnology companies, and academic institutions engaged in medicinal chemistry and nucleoside chemistry development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside-based therapeutics targeting viral infections and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates with modified sugar backbones.
• Biochemical Probe Development: Serves as a precursor for creating labeled or cross-linking nucleotide analogs for studying nucleic acid interactions and enzyme mechanisms.
• Antiviral Agent Synthesis: Intermediate in the production pathway for experimental antiviral compounds that mimic natural nucleosides.
• Academic & Industrial R&D: Fundamental reagent in organic synthesis and carbohydrate chemistry research within university and corporate R&D laboratories.

Basic Information

Product Name	1-(2,3-Epoxy-B-D-Lyxofuranosyl)Uracil
CAS No.	14042-38-7
Molecular Formula	C9H10N2O6
Molecular Weight	242.19 g/mol
Synonyms	1-(2,3-Anhydro-β-D-lyxofuranosyl)uracil; 2',3'-Epoxy-β-D-lyxofuranosyluracil; Uracil, 1-(2,3-anhydro-β-D-lyxofuranosyl)-; 1-(2,3-Anhydro-β-D-lyxofuranosyl)uracil; β-D-Lyxofuranoside, 2,3-anhydro-, 1-uracil; NSC 154042; 2,3-Epoxylyxofuranosyluracil
EINECS	Contact for details

Quality Control

Our 1-(2,3-Epoxy-B-D-Lyxofuranosyl)Uracil is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While typically supplied as a research-grade chemical, production can be aligned with GMP guidelines for advanced pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.