Description

1-Piperidinecarbonyl Chloride is a versatile and highly reactive organic intermediate, primarily used as a key building block in the synthesis of complex molecules. Its value lies in its ability to introduce the piperidinecarbonyl moiety, a crucial structural feature in many active pharmaceutical ingredients and agrochemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a precursor for amide and peptide bond formation.

Application

• Pharmaceutical Intermediate: Critical for synthesizing active pharmaceutical ingredients (APIs), particularly those containing piperidine-based structures, such as certain analgesics, antipsychotics, and nootropic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the piperidine ring enhances biological activity.
• Peptide Coupling Reagent: Acts as an efficient coupling agent in peptide synthesis for forming amide bonds between amino acids.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and novel chemical entities.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers and functional materials requiring specific amine-reactive groups.

Basic Information

Product Name	1-Piperidinecarbonyl Chloride
CAS No.	13939-69-0
Molecular Formula	C6H10ClNO
Molecular Weight	147.60 g/mol
Synonyms	Piperidine-1-carbonyl chloride; Piperidinecarbonyl chloride; 1-Carbamoylpiperidine chloride; Piperidinocarbonyl chloride; N-Carboxypiperidine chloride; Piperidine-1-carboxylic acid chloride; Isonipecotoyl chloride; N-(Chlorocarbonyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay, purity profiling, and identification, to ensure it meets the high standards required for pharmaceutical and fine chemical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic and highly volatile nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) and at controlled room temperature (15-25°C). Keep away from strong acids, bases, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.