Description

S-tert-Butyl Chlorothioformate, 96% is a versatile organosulfur reagent primarily used as a key building block in organic synthesis. This compound is valued for its role in introducing the tert-butylthio (t-BuS) protecting group and as a precursor for more complex sulfur-containing molecules. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sulfur-based functional groups.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the tert-butylthio moiety is a key structural component.
• Peptide Chemistry: Acts as a thiol-protecting group agent in solid-phase peptide synthesis (SPPS) to prevent unwanted side reactions.
• Polymer Modification: Employed in the synthesis and functionalization of polymers to impart specific chemical properties.
• Ligand and Catalyst Preparation: A precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and metal complexation.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	S-tert-Butyl Chlorothioformate, 96%
CAS No.	13889-95-7
Molecular Formula	C5H9ClOS
Molecular Weight	152.64 g/mol
Synonyms	Chloro-tert-butyl thioformate; tert-Butyl chlorothioformate; S-(tert-Butyl) chlorothioformate; Thiocarbonochloridic acid S-tert-butyl ester; t-Butyl chlorothioformate; Chlorothioformic acid S-tert-butyl ester; 1,1-Dimethylethyl chlorothioformate
EINECS	Contact for details

Quality Control

Our S-tert-Butyl Chlorothioformate, 96% is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC and HPLC to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong bases, oxidizing agents, and moisture. Due to its nature as a strong acid/organic solvent and highly volatile compound, it is recommended to store at controlled room temperature (15-25°C) under an inert atmosphere if possible. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 96.0%
Density (at 20°C)	~1.05 g/cm³
Refractive Index (n20D)	~1.47
Related Substances (GC)	≤ 4.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.