Description

1,4-Dihydro-3-β-D-Ribofuranosyl-7H-Pyrazolo[4,3-D]Pyrimidin-7-One CAS NO 13877-76-4 is a high-purity nucleoside analog with significant pharmaceutical research value. This compound is critical for its role as a key intermediate or reference standard in the development of novel antiviral and anticancer therapeutics. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced nucleoside-based active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the discovery and development of new antiviral agents targeting viral polymerases and replication mechanisms.
• Oncology Research: Investigated as a precursor or analog in the creation of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Functions as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and cellular signaling pathways.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Academic & Contract Research: Utilized in university and CRO settings for fundamental studies in medicinal chemistry and molecular biology.

Basic Information

Product Name	1,4-Dihydro-3-β-D-Ribofuranosyl-7H-Pyrazolo[4,3-D]Pyrimidin-7-One
CAS No.	13877-76-4
Molecular Formula	C9H12N4O5
Molecular Weight	256.22 g/mol
Synonyms	3-β-D-Ribofuranosyl-4,7-dihydro-7-oxopyrazolo[4,3-d]pyrimidine; 3-β-D-Ribofuranosyl-7H-pyrazolo[4,3-d]pyrimidin-7-one; 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-3-β-D-ribofuranosyl-; Ribofuranosylpyrazolopyrimidinone; NSC 401005; Pyrazolopyrimidine nucleoside
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency suitable for research and development. All material is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.