Description

(20R,14β,17α)-3β-Hydroxy-12α,20-Epoxy-5α-Pregnan-11-One CAS NO 13872-72-5 is a high-purity, synthetic steroid derivative characterized by its unique epoxy and ketone functional groups. This compound is a critical advanced intermediate in the synthesis of complex pharmaceutical agents, particularly within the steroid and hormone therapeutic classes. It is essential for research and development chemists and manufacturers in the pharmaceutical industry who require a reliable and high-quality building block for producing active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and development of new therapeutic agents targeting hormone receptors.
• Process Chemistry: Serves as a standardized building block in scale-up and optimization studies for commercial API manufacturing.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	(20R,14β,17α)-3β-Hydroxy-12α,20-Epoxy-5α-Pregnan-11-One
CAS No.	13872-72-5
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	3β-Hydroxy-12α,20-epoxy-5α-pregnan-11-one; 12α,20-Epoxy-3β-hydroxy-5α-pregnan-11-one; 20R,14β,17α-3β-Hydroxy-12α,20-epoxy-5α-pregnan-11-one; 11-Oxo-12α,20-epoxy-3β-hydroxy-5α-pregnane; 13872-72-5; Pregnan-11-one, 3β-hydroxy-12α,20-epoxy-, (5α,12α,14β,17α,20R)-; 12α,20α-Epoxy-3β-hydroxy-5α-pregnan-11-one (related isomer)
EINECS	Contact for details

Quality Control

Our (20R,14β,17α)-3β-Hydroxy-12α,20-Epoxy-5α-Pregnan-11-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.