Description

Thiophen-3-Yl-Acetyl Chloride is a versatile and highly reactive acid chloride derivative of thiophene, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 3-thienylacetyl moiety, enabling the construction of complex molecules with tailored properties. This intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing thiophene heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiophene ring contributes to biological activity.
• Material Science & Polymer Chemistry: Serves as a monomer or functionalization agent for creating conductive polymers, organic semiconductors, and specialty polymers.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Chemical Research & Development: A fundamental reagent for medicinal chemistry, exploring new structure-activity relationships and hit-to-lead optimization.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty additives.

Basic Information

Product Name	Thiophen-3-Yl-Acetyl Chloride
CAS No.	13781-65-2
Molecular Formula	C6H5ClOS
Molecular Weight	160.62 g/mol
Synonyms	3-Thienylacetyl Chloride; 3-Thiopheneacetyl Chloride; (3-Thienyl)acetyl Chloride; 2-(Thiophen-3-yl)acetyl Chloride; 3-Thiopheneglyoxylic Acid Chloride; 3-Thienylacetic Acid Chloride; 3-Thiopheneacetic Acid Chloride; 2-(3-Thienyl)acetyl Chloride
EINECS	Contact for details

Quality Control

Every batch of Thiophen-3-Yl-Acetyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. Our products undergo rigorous quality testing, including purity assay and impurity profiling, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.