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1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-4-(Hydroxyamino)Pyrimidin-2-One CAS NO 13491-41-3


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CAS No.:13491-41-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-4-(Hydroxymethyl)Pyrimidin-2-One is a high-purity nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate and building block in the creation of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of antiviral and anticancer drug candidates, where precise molecular structure and purity are critical.

Application

  • Pharmaceutical Intermediate: A crucial building block in the synthesis of novel nucleoside analog drugs.
  • Antiviral Research: Used in the development and study of potential antiviral agents targeting viral polymerases.
  • Oncology Drug Discovery: Serves as a precursor in the research of chemotherapeutic compounds that interfere with DNA/RNA synthesis.
  • Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
  • Precision Chemical Synthesis: Utilized in custom synthesis and medicinal chemistry for structure-activity relationship (SAR) studies.
  • Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name 1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-4-(Hydroxymethyl)Pyrimidin-2-One
CAS No. 13491-41-3
Molecular Formula C9H13N3O6
Molecular Weight 259.22 g/mol
Synonyms 4-(Hydroxymethyl)cytidine; 4-Hydroxymethylcytidine; hm5C; 1-(β-D-Ribofuranosyl)-4-(hydroxymethyl)-2(1H)-pyrimidinone; 4-Hydroxymethyl-1-β-D-ribofuranosyl-2(1H)-pyrimidinone; Cytidine, 4-(hydroxymethyl)-; 4-HMC; 4-Hydroxymethylcytidine ribonucleoside
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Quality Control

Our 1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-4-(Hydroxymethyl)Pyrimidin-2-One is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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