Description

2'-Deoxy Cyclic Gmp CAS NO 13440-33-0 is a specialized nucleotide analog and a key derivative of cyclic guanosine monophosphate (cGMP). This compound is of significant interest in biochemical research and pharmaceutical development due to its role in cell signaling pathways. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying cellular processes and developing novel therapeutic agents.

Application

• Biochemical Research: As a critical tool compound for investigating cyclic nucleotide signaling, second messenger systems, and enzyme kinetics.
• Pharmaceutical R&D: Serving as a reference standard, intermediate, or active pharmaceutical ingredient (API) in the development of cardiovascular, neurological, and metabolic disorder treatments.
• Enzyme Studies: Used as a substrate or inhibitor in assays for phosphodiesterases (PDEs), protein kinases, and other nucleotide-binding proteins.
• Cell Biology: Applied in studies of cell proliferation, differentiation, and apoptosis mechanisms mediated by cGMP-dependent pathways.
• Diagnostic Development: Potential use in the formulation of diagnostic kits and reagents for detecting specific enzymatic activities or biomarkers.

Basic Information

Product Name	2'-Deoxy Cyclic Gmp
CAS No.	13440-33-0
Molecular Formula	C10H12N5O6P
Molecular Weight	329.21 g/mol
Synonyms	2'-Deoxyguanosine 3',5'-cyclic monophosphate; 2'-Deoxy-cGMP; Deoxycyclic GMP; 2'-Deoxy-cyclic GMP; 2'-Deoxyguanosine cyclic 3',5'-(hydrogen phosphate); 2'-Deoxy-3',5'-cyclic GMP; 2'-d-cGMP; Cyclic 2'-deoxy-GMP
EINECS	Contact for details

Quality Control

Our 2'-Deoxy Cyclic Gmp is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.