Description

2-Chloro-N6,N6-Dimethyladenosine is a chemically modified nucleoside derivative of adenosine, featuring both chloro and dimethylamino substitutions. This compound is a critical pharmaceutical intermediate and a valuable research chemical for probing biochemical pathways. It is primarily utilized by pharmaceutical R&D teams and academic research institutions engaged in medicinal chemistry, enzymology, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of more complex nucleoside-based drug candidates and prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving adenosine receptors or modifying enzymes.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new antiviral or anticancer agents.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Chemical Biology Probes: Utilized in the design of molecular probes to study cellular signaling and metabolic pathways involving adenosine.

Basic Information

Product Name	2-Chloro-N6,N6-Dimethyladenosine
CAS No.	13406-53-6
Molecular Formula	C12H16ClN5O4
Molecular Weight	329.74 g/mol
Synonyms	2-Chloro-N6,N6-dimethyladenosine; 2-Chloro-N(6),N(6)-dimethyladenosine; 2-Chloro-6-(dimethylamino)purine riboside; 9-β-D-Ribofuranosyl-2-chloro-6-(dimethylamino)purine; 2-Cl-N6,N6-DMA; 2-Chloro-6-dimethylaminopurine riboside; Adenosine, 2-chloro-N6,N6-dimethyl-
EINECS	Contact for details

Quality Control

Our 2-Chloro-N6,N6-Dimethyladenosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.