Description

N6-Methyl-2-Methylthioadenosine is a chemically modified nucleoside derivative of adenosine, distinguished by methylation at the N6 position and a methylthio substitution at the 2' position. This specific structural modification makes it a valuable biochemical tool and a key intermediate in the research and synthesis of nucleotide analogs. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, enzymology, and molecular biology. The compound is offered with a commitment to high purity and reliable supply chain integrity for critical research and production applications.

Application

• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies, particularly for methyltransferase and adenosine deaminase research.
• Pharmaceutical Intermediates: Acts as a key building block in the synthesis of novel nucleoside-based therapeutics and prodrugs.
• Metabolic Pathway Analysis: Used as a tracer or standard in studying purine and methionine salvage pathways.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC and LC-MS.
• Enzyme Mechanism Studies: Investigates the role of specific functional groups in substrate recognition and catalysis.
• Antiviral & Anticancer Agent Development: Explored as a precursor for modified nucleosides with potential biological activity.

Basic Information

Product Name	N6-Methyl-2-Methylthioadenosine
CAS No.	13406-51-4
Molecular Formula	C₁₂H₁₇N₅O₄S
Molecular Weight	327.36 g/mol
Synonyms	2-Methylthio-N6-methyladenosine; N6-Methyl-2-methylthioadenosine; 2-Methylthio-N(6)-methyladenosine; 6-Methylamino-9-(5-O-phosphono-β-D-ribofuranosyl)purine-2-thiol methyl ester (related); 2-(Methylthio)-N6-methyladenosine; N(6)-Methyl-2-methylthioadenosine; 2-MeS(6)-MeA; NSC 154032
EINECS	Contact for details

Quality Control

Our N6-Methyl-2-Methylthioadenosine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay (HPLC), related substances, and residual solvents. We adhere to stringent internal quality standards to support your research and development needs. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.