Description

Adenosine, 2-Chloro-n-Methyl- CAS NO 13406-50-3 is a chemically modified nucleoside derivative, specifically a chlorinated and N-methylated analog of adenosine. This modification imparts unique biochemical properties, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for synthesizing novel therapeutic agents, enzyme inhibitors, and as a key building block in nucleotide chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel adenosine receptor ligands and targeted therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and signaling pathways.
• Nucleoside Analogue Development: Acts as a building block for creating modified nucleosides with potential antiviral or anticancer activity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying protein-nucleic acid interactions.
• Process Development: Utilized in process chemistry for scaling up the production of specialty nucleotide-based Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	Adenosine, 2-Chloro-n-Methyl-
CAS No.	13406-50-3
Molecular Formula	C11H14ClN5O4
Molecular Weight	315.71 g/mol
Synonyms	2-Chloro-N-methyladenosine; 2-Chloro-1-methyladenosine; 9-β-D-Ribofuranosyl-2-chloro-6-methylaminopurine; 2-Chloro-6-(methylamino)-9-β-D-ribofuranosyl-9H-purine; N-Methyl-2-chloroadenosine; 2-Cl-N-Me-Ado
EINECS	Contact for details

Quality Control

Our Adenosine, 2-Chloro-n-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.