Description

8-Amino-2'-Deoxyadenosine is a modified nucleoside derivative of deoxyadenosine, featuring an amino group substitution at the 8-position of the purine ring. This structural modification makes it a valuable biochemical building block and research tool for studying nucleic acid structure, function, and enzyme interactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleotide chemistry, molecular biology, and the development of novel therapeutic agents.

Application

• Biochemical Research: Serves as a critical precursor or intermediate in the synthesis of modified oligonucleotides for structure-activity relationship (SAR) studies.
• Enzymology Studies: Used as a substrate or inhibitor to probe the active sites and mechanisms of nucleoside/nucleotide-processing enzymes like kinases and polymerases.
• Antiviral/Anticancer Agent Development: Investigated as a scaffold for the design of nucleoside analogs with potential therapeutic activity.
• Diagnostic Probe Synthesis: Employed in the creation of labeled nucleotides for use in various detection and diagnostic assays.
• Academic Research: Fundamental tool in university and institutional labs for exploring DNA damage, repair mechanisms, and epigenetic modifications.

Basic Information

Product Name	8-Amino-2'-Deoxyadenosine
CAS No.	13389-09-8
Molecular Formula	C10H14N6O3
Molecular Weight	266.26 g/mol
Synonyms	8-Amino-2'-deoxyadenosine; 8-Aminodeoxyadenosine; 2'-Deoxy-8-aminoadenosine; 8-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)adenine; 8-NH2-dA; 8-Amino-dA; 8-Aminoadenine deoxyriboside
EINECS	Contact for details

Quality Control

Our 8-Amino-2'-Deoxyadenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.