Description

3'-(Acetylamino)-3'-Deoxy-N,n-Dimethyladenosine 2',5'-Diacetate is a chemically modified nucleoside derivative, primarily utilized as a critical intermediate in advanced pharmaceutical research and synthesis. This compound is valued for its role in the development of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It serves as a key building block for researchers and manufacturers in the pharmaceutical and biotechnology industries seeking to create modified RNA/DNA analogs with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate RNA modification pathways and polymerase activity.
• Pro-drug Synthesis: Serves as a protected or modified form of adenosine for the creation of pro-drug candidates with improved bioavailability or stability.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore the impact of acetylamino and acetate modifications on nucleoside pharmacology.
• Labeled Compound Production: Can be used as a starting point for synthesizing isotopically labeled (e.g., C13, N15) nucleosides for metabolic tracing and pharmacokinetic studies.

Basic Information

Product Name	3'-(Acetylamino)-3'-Deoxy-N,n-Dimethyladenosine 2',5'-Diacetate
CAS No.	13347-33-6
Molecular Formula	C₁₈H₂₄N₆O₇
Molecular Weight	436.42 g/mol
Synonyms	3'-Acetamido-3'-deoxy-N,N-dimethyladenosine 2',5'-diacetate; 3'-(Acetylamino)-3'-deoxy-N,N-dimethyladenosine 2',5'-diacetate; N,N-Dimethyl-3'-(acetylamino)-3'-deoxyadenosine 2',5'-diacetate; 3'-Deoxy-3'-(acetylamino)-N,N-dimethyladenosine 2',5'-diacetate; 2',5'-Di-O-acetyl-3'-(acetylamino)-3'-deoxy-N,N-dimethyladenosine; Modified Adenosine Derivative; Nucleoside Intermediate 13347-33-6
EINECS	Contact for details

Quality Control

Our 3'-(Acetylamino)-3'-Deoxy-N,n-Dimethyladenosine 2',5'-Diacetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or cGMP guidelines, where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.