Description

3-Nitrobenzoyl Bromide is a versatile and highly reactive aromatic acyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 3-nitrobenzoyl moiety, a key functional group for constructing complex molecules with specific electronic and steric properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create active ingredients, ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring nitroaromatic pharmacophores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the nitrobenzoyl group contributes to biological activity.
• Peptide Coupling Reagent: Acts as an efficient coupling agent or activated ester precursor in peptide and amide bond formation.
• Ligand and Catalyst Preparation: Employed to synthesize complex ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Polymer Modification: Functionalizes polymers and resins to impart specific chemical properties or reactivity.
• Dye and Pigment Manufacturing: Serves as an intermediate in the synthesis of nitroaromatic dyes and organic pigments.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-Nitrobenzoyl Bromide
CAS No.	13277-62-8
Molecular Formula	C7H4BrNO3
Molecular Weight	230.02 g/mol
Synonyms	m-Nitrobenzoyl Bromide; 3-Nitrobenzoic Acid Bromide; Benzoic acid, 3-nitro-, bromide; m-Nitrobenzoic Acid Bromide; 3-Nitrobenzoyl Bromide; (3-Nitrobenzoyl) bromide; Bromo(3-nitrophenyl)methanone
EINECS	Contact for details

Quality Control

Our 3-Nitrobenzoyl Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards where applicable, supporting its use in regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.