Description

4-Trimethylsiloxy-3-Penten-2-One is a versatile organosilicon compound used as a key intermediate and protecting group reagent in advanced organic synthesis. Its value lies in its ability to act as a masked β-diketone or acetoacetate equivalent, enabling complex transformations under mild conditions. This product is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking efficient synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides requiring specific ketone functionalities.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and performance chemicals.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new carbon-carbon bond forming reactions.
• Polymer Chemistry: Potential monomer or modifier in the synthesis of specialized silicone-containing polymers.
• Protecting Group Chemistry: The trimethylsilyl (TMS) group acts as a protective moiety for sensitive carbonyl groups during multi-step syntheses.

Basic Information

Product Name	4-Trimethylsiloxy-3-Penten-2-One
CAS No.	13257-81-3
Molecular Formula	C8H16O2Si
Molecular Weight	172.30 g/mol
Synonyms	3-Penten-2-one, 4-(trimethylsiloxy)-; 4-(Trimethylsilyloxy)-3-penten-2-one; Acetylacetone trimethylsilyl enol ether; TMS enol ether of acetylacetone; 4-Trimethylsilyloxy-3-penten-2-one; 4-(Trimethylsiloxy)-3-penten-2-one; 4-TMS-oxy-3-penten-2-one; 13257-81-3
EINECS	Contact for details

Quality Control

Our 4-Trimethylsiloxy-3-Penten-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.