Description

2,4-Dithiouridine is a modified nucleoside derivative of uridine, where two thiol groups replace oxygen atoms at the 2 and 4 positions of the pyrimidine ring. This unique structure makes it a valuable intermediate and building block in organic synthesis and biochemical research. It is primarily utilized in the development of novel nucleoside analogs for pharmaceutical research and as a key reagent in studying RNA structure and function. Industries involved in advanced life science research, antiviral drug discovery, and specialty chemical synthesis will find this compound essential for their innovative projects.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a tool compound to study RNA modification, structure, and thiol-mediated redox processes in nucleic acids.
• Proteomics & Diagnostics: Can be employed in the development of cross-linking agents or probes for labeling and detecting biomolecules.
• Organic Synthesis: Acts as a versatile building block for constructing complex heterocyclic compounds and specialty fine chemicals.
• Material Science: Potential applications in creating functionalized surfaces or polymers with specific nucleoside-based recognition properties.

Basic Information

Product Name	2,4-Dithiouridine
CAS No.	13239-96-8
Molecular Formula	C9H12N2O5S2
Molecular Weight	292.33 g/mol
Synonyms	2,4-Dithio-1-β-D-ribofuranosyluracil; 2,4-Dithiouridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dithioxo-1,2,3,4-tetrahydropyrimidine; 2,4-Dithio-uridine; 2,4-Disulfanyluridine; Uridine, 2,4-dithio-; β-D-Ribofuranoside, 2,4-dithio-1H-pyrimidin-1-yl
EINECS	Contact for details

Quality Control

Our 2,4-Dithiouridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and residual solvents is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.