Description

Ara-C Triphosphate CAS NO 13191-15-6 is the active triphosphate metabolite of the nucleoside analog cytarabine, a critical compound in biochemical and pharmaceutical research. This high-purity nucleotide is essential for studying DNA synthesis inhibition and cellular mechanisms of action. It is primarily utilized by researchers and manufacturers in the fields of oncology research, antiviral studies, and molecular biology for in vitro and cell-based assays.

Application

• Oncology Research: Used as a reference standard and active agent in studies investigating the mechanism of cytarabine (Ara-C) in leukemia and other cancers.
• Biochemical Assays: Serves as a substrate for DNA polymerases in enzymatic studies to understand nucleotide incorporation and chain termination.
• Antiviral Research: Employed in research exploring the inhibition of viral DNA replication.
• Cell Signaling Studies: Utilized to investigate intracellular metabolism and the activation pathways of nucleoside analog prodrugs.
• Pharmaceutical Development: Acts as a key intermediate and analytical standard in the development and quality control of cytarabine-based therapeutics.
• Academic Research: Fundamental tool in university and institutional labs for molecular pharmacology and cancer biology projects.

Basic Information

Product Name	Ara-C Triphosphate
CAS No.	13191-15-6
Molecular Formula	C9H16N3O14P3
Molecular Weight	507.15 g/mol
Synonyms	Cytarabine Triphosphate; 1-β-D-Arabinofuranosylcytosine 5'-Triphosphate; Cytosine Arabinoside Triphosphate; Ara-CTP; Cytosine-β-D-arabinofuranoside 5'-triphosphate; Cytarabine 5'-triphosphate; 1-β-D-Arabinofuranosylcytosine 5'-(tetrahydrogen triphosphate)
EINECS	Contact for details

Quality Control

Our Ara-C Triphosphate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.