Description

2-(Hydroxymethyl)-5-(6-Methylsulfanylpurin-9-Yl)Oxolane-3,4-Diol is a high-purity nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for their most sensitive applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and cancer.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, metabolic pathway analysis, and molecular biology research.
• Antiviral Drug Development: Serves as a core scaffold for developing prodrugs and active pharmaceutical ingredients (APIs) with potential activity against a range of viruses.
• Oncology Research: Investigated for its role in creating chemotherapeutic agents that interfere with DNA/RNA synthesis in rapidly dividing cells.
• Process Development & Scale-up: Employed in process chemistry for the optimization and commercial-scale production of related active compounds.
• Analytical Standard: Provides a high-purity benchmark for quality control (QC) and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.

Basic Information

Product Name	2-(Hydroxymethyl)-5-(6-Methylsulfanylpurin-9-Yl)Oxolane-3,4-Diol
CAS No.	13153-62-3
Molecular Formula	C11H14N4O4S
Molecular Weight	298.32 g/mol
Synonyms	6-Methylmercaptopurine Riboside; 6-Methylthio-9-β-D-ribofuranosylpurine; 6-Methylthiopurine Ribonucleoside; 6-Methylthio-9-β-D-ribofuranosyl-9H-purine; 6-(Methylthio)-9-β-D-ribofuranosyl-9H-purine; 6-MMPR; NSC-40774; 9H-Purine, 6-(methylthio)-, 9-β-D-ribofuranosyl-
EINECS	Contact for details

Quality Control

Our 2-(Hydroxymethyl)-5-(6-Methylsulfanylpurin-9-Yl)Oxolane-3,4-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.