Description

2-[2-Amino-6-(Pyridin-2-Ylmethylsulfanyl)Purin-9-Yl]-5-(Hydroxymethyl) Oxolane-3,4-Diol is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound, with CAS number 13153-28-1, serves as a critical building block for the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular signaling pathways. It is essential for research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the discovery and development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside-based antiviral drugs and chemotherapeutic agents.
• Antiviral Research: Used in the development of compounds targeting viruses such as hepatitis B (HBV), hepatitis C (HCV), and herpesviruses.
• Oncology Research: Serves as a scaffold for creating novel nucleoside analogs that inhibit cancer cell proliferation.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor for various nucleoside-processing enzymes.
• Prodrug Development: Utilized in the design of prodrugs to enhance the bioavailability and targeting of active pharmaceutical ingredients (APIs).
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2-[2-Amino-6-(Pyridin-2-Ylmethylsulfanyl)Purin-9-Yl]-5-(Hydroxymethyl) Oxolane-3,4-Diol
CAS No.	13153-28-1
Molecular Formula	C₁₆H₁₈N₆O₄S
Molecular Weight	390.42 g/mol
Synonyms	2-Amino-6-[(2-pyridinylmethyl)thio]-9H-purin-9-yl-5-(hydroxymethyl)tetrahydro-3,4-furandiol; 2-Amino-6-(pyridin-2-ylmethylsulfanyl)-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purine; 6-[(2-Pyridinylmethyl)thio]-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-9H-purin-2-amine; Nucleoside analog intermediate; Pyridinylmethylthio purine nucleoside.
EINECS	Contact for details

Quality Control

Our 2-[2-Amino-6-(Pyridin-2-Ylmethylsulfanyl)Purin-9-Yl]-5-(Hydroxymethyl) Oxolane-3,4-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with research-grade and potential GMP starting material standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.