Description

3β,17β-Bis(Trimethylsilyloxy)Androst-5-Ene is a key steroidal intermediate featuring trimethylsilyl (TMS) protecting groups on its hydroxyl functions. This compound is critical for enabling selective synthetic transformations in complex organic and pharmaceutical chemistry. It is primarily utilized by research institutions and manufacturers engaged in the development and production of steroid-based active pharmaceutical ingredients (APIs) and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of steroidal drugs and hormones.
• Organic Synthesis: Used as a protected precursor for the selective functionalization of the androstane skeleton in research and development.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid metabolism, receptor binding, and enzyme inhibition.
• Process Chemistry: Facilitates scalable and efficient manufacturing routes for complex steroid derivatives in pilot and commercial production.

Basic Information

Product Name	3β,17β-Bis(Trimethylsilyloxy)Androst-5-Ene
CAS No.	13110-76-4
Molecular Formula	C25H46O2Si2
Molecular Weight	434.81 g/mol
Synonyms	Androst-5-ene-3β,17β-diol bis(trimethylsilyl) ether; 3β,17β-Bis(trimethylsiloxy)androst-5-ene; 3β,17β-Bis-O-(trimethylsilyl)androst-5-ene; 5-Androstene-3β,17β-diol bis(trimethylsilyl) ether; 3β,17β-Di-O-trimethylsilylandrost-5-ene; Androst-5-ene-3β,17β-diol, bis(trimethylsilyl) ether; TMS ether of Androst-5-ene-3β,17β-diol
EINECS	Contact for details

Quality Control

Our 3β,17β-Bis(Trimethylsilyloxy)Androst-5-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.