Description

Guanosine 3'-Diphosphoric Acid is a high-purity nucleotide derivative essential for biochemical research and pharmaceutical development. This compound serves as a critical building block and substrate in enzymatic studies, particularly those involving RNA synthesis and nucleotide metabolism. It is primarily utilized by research institutions, diagnostic manufacturers, and biotechnology companies focused on molecular biology, enzymology, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a substrate or intermediate in enzymatic assays and studies of nucleotide metabolism, RNA synthesis, and kinase/phosphatase activity.
• Pharmaceutical Development: Serves as a key precursor or reference standard in the research and development of antiviral drugs, cancer therapeutics, and other nucleotide-based pharmaceuticals.
• Diagnostic Reagent Manufacturing: Incorporated into the formulation of diagnostic kits and reagents for clinical testing and molecular diagnostics.
• Enzymology Studies: Essential for investigating the mechanisms and kinetics of enzymes like RNA polymerases, nucleotidyltransferases, and other phosphotransferases.
• Cell Signaling Research: Applied in studies of intracellular signaling pathways where nucleotide derivatives act as secondary messengers or regulators.
• Academic & Industrial R&D: A fundamental reagent for universities, contract research organizations (CROs), and biotech firms engaged in life science research.

Basic Information

Product Name	Guanosine 3'-Diphosphoric Acid
CAS No.	13098-76-5
Molecular Formula	C10H15N5O11P2
Molecular Weight	443.20 g/mol
Synonyms	3'-GDP; Guanosine-3'-diphosphate; GDP-3'; 3'-Guanosine diphosphate; Guanosine 3'-pyrophosphate; 3'-Guanosine 5'-diphosphate; Guanosine 3'-diphosphate sodium salt (common salt form); 9-β-D-Ribofuranosylguanine 3'-diphosphate
EINECS	Contact for details

Quality Control

Our Guanosine 3'-Diphosphoric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For short-term use, store in a desiccator at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.