Description

1-Methyl-N(4)-Ureidocytosine is a modified nucleobase derivative of cytosine, featuring a methyl group at the N1 position and a ureido substituent at the N4 position. This specific molecular architecture makes it a valuable synthetic intermediate and building block in advanced organic and medicinal chemistry research. It is primarily sought after by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel nucleoside analogs and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies exploring enzyme-substrate interactions, particularly with cytidine deaminases and other nucleoside-metabolizing enzymes.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Nucleic Acid Chemistry: Employed in the development of modified oligonucleotides for diagnostic and therapeutic applications.
• Chemical Biology Probes: Utilized to create labeled or tagged compounds for investigating biological pathways and mechanisms.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-Methyl-N(4)-Ureidocytosine
CAS No.	13085-53-5
Molecular Formula	C6H9N5O2
Molecular Weight	183.17 g/mol
Synonyms	1-Methyl-4-ureidocytosine; 1-Methyl-4-ureido-2(1H)-pyrimidinone; 4-Ureido-1-methylcytosine; 1-Methyl-4-ureido-2-oxo-1,2-dihydropyrimidine; N4-Carbamoyl-1-methylcytosine; 1-Methylisocytosine-4-urea; 1-Methyl-N4-carbamoylcytosine
EINECS	Contact for details

Quality Control

Our 1-Methyl-N(4)-Ureidocytosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). The product should be kept under inert conditions if long-term stability is a concern.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.