Description

N(4), O(2')-Dimethylcytidine is a chemically modified nucleoside derivative, specifically a dimethylated analog of cytidine. This modification is critical for research into nucleic acid structure, function, and stability, as it alters base-pairing properties and resistance to enzymatic degradation. It serves as a valuable building block and reference standard for pharmaceutical R&D, particularly in the development of antiviral and anticancer nucleoside analogs, as well as for academic studies in biochemistry and molecular biology.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of novel antiviral and anticancer therapeutic agents.
• Biochemical Research: Used as a modified nucleoside probe to study RNA structure, function, and enzyme-substrate interactions.
• Antisense Oligonucleotide Development: Incorporated into oligonucleotide sequences to enhance stability against nucleases and modulate binding affinity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical and research laboratories.
• Academic Research: Fundamental tool for investigating nucleoside metabolism, epigenetic modifications, and nucleic acid chemistry.

Basic Information

Product Name	N(4), O(2')-Dimethylcytidine
CAS No.	13048-95-8
Molecular Formula	C11H17N3O5
Molecular Weight	271.27 g/mol
Synonyms	2'-O-Methyl-N4-methylcytidine; 1-(2-O-Methyl-β-D-ribofuranosyl)-4-methylamino-2(1H)-pyrimidinone; 4-Methylamino-1-(2-O-methyl-β-D-ribofuranosyl)pyrimidin-2(1H)-one; N4-Methyl-2'-O-methylcytidine; 2'-O-Methyl-N(4)-methylcytidine; Modified Cytidine Derivative; N4,2'-O-Dimethylcytidine
EINECS	Contact for details

Quality Control

Our N(4), O(2')-Dimethylcytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.