Description

5-Formamidoimidazole-4-Carboxamide Ribotide is a key biochemical intermediate, specifically a ribonucleotide derivative, essential in the biosynthesis of purine nucleotides. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in nucleotide metabolism pathways. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in metabolic studies, enzyme research, and the development of nucleotide-based therapeutics.

Application

• Biochemical Research: Critical intermediate for studying the de novo purine biosynthesis pathway and related enzymatic mechanisms.
• Pharmaceutical Development: Serves as a precursor or reference standard in the research and synthesis of novel nucleotide analogs and potential chemotherapeutic agents.
• Enzymology Studies: Used as a substrate or inhibitor in assays to characterize the activity of enzymes like phosphoribosylformylglycinamidine cyclo-ligase (FGAM cyclase) within the purine synthesis cascade.
• Metabolic Pathway Analysis: Employed in tracer studies and metabolic flux analysis to understand cellular nucleotide metabolism under various physiological or pathological conditions.
• Reference Standard: High-purity grade is essential for analytical method development, validation, and quality control in pharmaceutical and research laboratories.

Basic Information

Product Name	5-Formamidoimidazole-4-Carboxamide Ribotide
CAS No.	13018-54-7
Molecular Formula	C11H16N5O10P
Molecular Weight	409.25 g/mol
Synonyms	5-Formamido-1-(5-O-phosphono-β-D-ribofuranosyl)imidazole-4-carboxamide; FAICAR; 5'-Phosphoribosyl-5-formamido-4-imidazolecarboxamide; 5-Formamidoimidazole-4-carboxamide ribonucleotide; 5'-Phosphoribosyl-5-formamido-4-imidazolecarboxamide; 5-Aminoimidazole-4-carboxamide ribotide formyl derivative; (5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
EINECS	Contact for details

Quality Control

Our 5-Formamidoimidazole-4-Carboxamide Ribotide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for biochemical reagents to support your research and development needs with reliable material.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.