Description

Adenosine 5'-Monophosphate 2',3'-Dialdehyde is a chemically modified nucleotide derivative where the ribose sugar moiety has been oxidized to a dialdehyde. This compound serves as a crucial intermediate and cross-linking agent in biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications such as nucleic acid modification, enzyme inhibition studies, and the synthesis of advanced molecular probes.

Application

• Biochemical Cross-linking Agent: Used to covalently modify and cross-link proteins, enzymes, and nucleic acids for structural and functional studies.
• Enzyme Inhibitor Synthesis: Acts as a key intermediate in the development of potent, irreversible inhibitors for nucleoside-metabolizing enzymes.
• Nucleic Acid Research: Employed in the chemical modification of RNA and DNA to study structure-function relationships and develop novel diagnostic tools.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of nucleotide-based prodrugs and antiviral agents.
• Affinity Chromatography: Used to prepare immobilized ligands for the purification of specific proteins and enzymes.
• Bioconjugation: Facilitates the attachment of reporter molecules (e.g., fluorophores, biotin) to biomolecules for detection and analysis.

Basic Information

Product Name	Adenosine 5'-Monophosphate 2',3'-Dialdehyde
CAS No.	13011-02-4
Molecular Formula	C10H12N5O8P
Molecular Weight	361.21 g/mol
Synonyms	2',3'-Dialdehyde Adenosine 5'-Monophosphate; Periodate-Oxidized AMP; o-AMP; AMP Dialdehyde; Adenosine-5'-monophosphodialdehyde; 5'-AMP-2',3'-dialdehyde; Oxidized Adenosine Monophosphate; 5'-Adenylic Acid Dialdehyde
EINECS	Contact for details

Quality Control

Our Adenosine 5'-Monophosphate 2',3'-Dialdehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets high-purity research standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.