Description

Cytidine, N,n-Dimethyl- is a modified nucleoside derivative where both amino groups on the cytosine base are methylated. This chemical modification is crucial for research in nucleic acid chemistry and epigenetics, as it alters base-pairing interactions and stability. It serves as a valuable building block and reference standard for pharmaceutical R&D, particularly in the development of nucleoside-based therapeutics and diagnostic probes for the life science and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving methyltransferases and other nucleic acid-modifying enzymes.
• Epigenetics Studies: Serves as a reference compound for investigating DNA and RNA methylation patterns and their biological implications.
• Diagnostic Probe Development: Utilized in the design and synthesis of labeled probes for genetic testing and molecular diagnostics.
• Life Science Reagents: Incorporated into specialized cell culture media or buffers for advanced cellular and molecular biology applications.
• Standards & Calibration: Provides a high-purity analytical standard for quality control and method validation in HPLC, LC-MS, and NMR analyses.

Basic Information

Product Name	Cytidine, N,n-Dimethyl-
CAS No.	13007-43-7
Molecular Formula	C11H17N3O5
Molecular Weight	271.27 g/mol
Synonyms	N,N-Dimethylcytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2(1H)-pyrimidinone, N,N-dimethyl-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(dimethylamino)pyrimidin-2(1H)-one; 4-(Dimethylamino)-1-β-D-ribofuranosyl-2(1H)-pyrimidinone; DM-Cytidine
EINECS	Contact for details

Quality Control

Our Cytidine, N,n-Dimethyl- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.