Description

3-Methoxyestra-1,3,5(10)-Triene-11α,17β-Diol CAS NO 10516-35-5 is a high-purity, synthetic steroid derivative, specifically an 11α-hydroxy metabolite of 3-methoxyestradiol. This compound is valued for its role as a critical pharmaceutical intermediate and a reference standard in advanced research and development. It is primarily required by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the synthesis of novel therapeutic agents and in-depth metabolic studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or analytical standard in studies of estrogen metabolism, enzyme activity, and steroid hormone pathways.
• Metabolite Standard: Essential for the identification and quantification of 3-methoxyestradiol metabolites in pharmacokinetic and pharmacodynamic studies.
• Academic & Institutional Research: Employed in university and institutional labs for investigating steroid biochemistry and endocrinology.
• Method Development & Validation: Serves as a calibrant in developing and validating analytical methods such as HPLC, LC-MS, and GC-MS.
• Preclinical Studies: Utilized in in vitro and in vivo models to explore biological activity and therapeutic potential.

Basic Information

Product Name	3-Methoxyestra-1,3,5(10)-Triene-11α,17β-Diol
CAS No.	10516-35-5
Molecular Formula	C19H26O3
Molecular Weight	302.41 g/mol
Synonyms	11α-Hydroxy-3-methoxyestradiol; 3-Methoxy-11α,17β-estratriene-3,17-diol; 3-Methoxy-11α,17β-estradiol; 11α-Hydroxy-3-methoxyestra-1,3,5(10)-triene-17β-ol; 3-MeO-11α-OH-E2; 11α-Hydroxy-3-methoxy-E2
EINECS	Contact for details

Quality Control

Our 3-Methoxyestra-1,3,5(10)-Triene-11α,17β-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting specifications for research and pharmaceutical use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.