Description

5-[(2S)-1-Methyl-2α-Pyrrolidinyl]Pyridine-2-Ol is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where stereochemical control is critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Catalyst Ligand Preparation: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring precise molecular architecture.
• Academic & Industrial Research: A valuable compound for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	5-[(2S)-1-Methyl-2α-Pyrrolidinyl]Pyridine-2-Ol
CAS No.	10516-09-3
Molecular Formula	C11H16N2O
Molecular Weight	192.26 g/mol
Synonyms	(S)-5-(1-Methyl-2-pyrrolidinyl)-2-pyridinol; (S)-5-(1-Methylpyrrolidin-2-yl)pyridin-2-ol; 2-Pyridinol, 5-[(2S)-1-methyl-2-pyrrolidinyl]-; (S)-5-(N-Methyl-2-pyrrolidinyl)-2-pyridinol; (S)-5-(1-Methyl-2-pyrrolidinyl)-2-hydroxypyridine; (2S)-1-Methyl-2-(6-hydroxy-3-pyridinyl)pyrrolidine; 10516-09-3
EINECS	Contact for details

Quality Control

Our 5-[(2S)-1-Methyl-2α-Pyrrolidinyl]Pyridine-2-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.