Description

3-Nitrophenyl Chlorothioformate is a specialized organic intermediate characterized by its reactive chlorothioformate and nitro-substituted phenyl group. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing thioester or thiocarbamate functionalities.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity for structure-activity relationship (SAR) studies.
• Peptide Chemistry & Bioconjugation: Serves as a coupling agent or protecting group reagent in peptide synthesis and for labeling biomolecules.
• Polymer & Material Science: Employed as a monomer or modifying agent to create polymers with specific thermal or chemical resistance properties.
• Chemical Research & Development: A versatile building block for organic synthesis, enabling the creation of libraries of compounds for screening in various discovery programs.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the nitro and sulfur-containing groups impart specific coloristic properties.

Basic Information

Product Name	3-Nitrophenyl Chlorothioformate
CAS No.	10506-34-0
Molecular Formula	C7H4ClNO3S
Molecular Weight	217.63 g/mol
Synonyms	3-Nitrophenyl Chlorothioformate; m-Nitrophenyl Chlorothioformate; Chlorothioformic Acid O-(3-Nitrophenyl) Ester; 3-Nitrobenzenol Chlorothioformate; 3-Nitrophenyl Chlorosulfenylformate; (3-Nitrophenoxy)carbonothioic Chloride; Phenyl Chlorothioformate, 3-nitro-; NSC 403142
EINECS	Contact for details

Quality Control

Our 3-Nitrophenyl Chlorothioformate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.