Description

2-Pentanone, 5,5,5-Trifluoro-4-Hydroxy-4-(Trifluoromethyl)- is a highly fluorinated ketone derivative, a specialized building block valued for its unique trifluoromethyl and hydroxyl functionalities. This compound is critical for introducing lipophilicity and metabolic stability into target molecules, making it a sought-after intermediate in advanced chemical synthesis. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where fluorine substitution enhances biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers and coatings with specific surface properties.
• Organic Synthesis Building Block: Employed in medicinal and combinatorial chemistry for constructing complex, fluorinated molecular architectures.
• Liquid Crystal & Electronic Chemical Intermediate: Potential use in the synthesis of fluorinated components for display and semiconductor materials.

Basic Information

Product Name	2-Pentanone, 5,5,5-Trifluoro-4-Hydroxy-4-(Trifluoromethyl)-
CAS No.	10487-10-2
Molecular Formula	C6H6F6O2
Molecular Weight	224.10 g/mol
Synonyms	5,5,5-Trifluoro-4-hydroxy-4-(trifluoromethyl)pentan-2-one; 1,1,1-Trifluoro-2-(trifluoromethyl)-4-oxopentan-2-ol; 4-Hydroxy-4-(trifluoromethyl)-5,5,5-trifluoropentan-2-one; Hexafluoro-tert-butyl alcohol methyl ketone; α,α,α,α',α',α'-Hexafluoro-β-hydroxy-β-methylbutyrophenone precursor; HFA (Hexafluoroacetone) derivative ketone; Perfluoro-tert-butyl alcohol ketone
EINECS	Contact for details

Quality Control

Our 2-Pentanone, 5,5,5-Trifluoro-4-Hydroxy-4-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and scale-up activities with reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.