Description

5α-Androstane-4,17-Dione is a key steroid intermediate and reference standard of significant importance in pharmaceutical research and development. This compound serves as a crucial building block for the synthesis of various steroid hormones and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in steroid chemistry, metabolic studies, and the production of high-value therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and starting material in metabolic pathway studies, enzyme inhibition assays, and steroidogenesis research.
• Reference Standard: Serves as a high-purity analytical standard for quality control (QC) and method development in pharmaceutical laboratories.
• Hormone Analog Development: A foundational scaffold for the research and development of novel androgen and steroid hormone receptor modulators.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized steroid derivatives.

Basic Information

Product Name	5α-Androstane-4,17-Dione
CAS No.	10455-14-8
Molecular Formula	C19H28O2
Molecular Weight	288.43 g/mol
Synonyms	5α-Androstanedione; 4,17-Androstanedione; 5α-Androstane-4,17-dione; NSC 11336; Androstanedione; Etiocholanedione; 17-Ketoetiocholane; 5α-Etiocholane-3,17-dione
EINECS	233-946-4

Quality Control

Our 5α-Androstane-4,17-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.