Description

Uridylyl-(2'-5')-Adenosine is a specialized dinucleoside monophosphate, a key structural motif in oligonucleotide chemistry and biochemistry. This compound is of significant interest for its role as a model system and intermediate in the synthesis of complex oligonucleotides and for studying RNA structure and function. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, diagnostic reagent production, and advanced life science research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleotide-based therapeutics, including antisense oligonucleotides and other RNA-targeting drugs.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, particularly those involving RNA ligases, nucleases, and other nucleic acid-modifying enzymes.
• Diagnostic Development: Employed in the design and production of probes and primers for molecular diagnostics and next-generation sequencing applications.
• Life Science Reagents: A key component in the formulation of high-purity reagents for genomics, transcriptomics, and proteomics research workflows.
• Academic Research: Utilized in university and institutional labs for fundamental studies on nucleic acid structure, stability, and intermolecular interactions.

Basic Information

Product Name	Uridylyl-(2'-5')-Adenosine
CAS No.	10453-52-8
Molecular Formula	C19H23N7O13P
Molecular Weight	588.40 g/mol
Synonyms	2'-5'-UpA; Uridylyl(2'→5')adenosine; Adenosine, 5'-[3-(1-β-D-ribofuranosyluracil-5-yl)dihydrogen diphosphate]; 2'-5'-Linked UpA; pU(2'-5')pA; 2',5'-Oligoadenylate Core; 2-5A Core; 2'-5' Adenyluridylate
EINECS	Contact for details

Quality Control

Our Uridylyl-(2'-5')-Adenosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure the material meets the stringent requirements for research and cGMP manufacturing. Specifications are aligned with industry standards for high-purity biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 10 EU/mg
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.