Description

3α-Acetyloxy-7-Oxo-5β-Cholan-24-Oic Acid Methyl Ester is a high-purity steroidal intermediate of significant importance in pharmaceutical synthesis. This compound matters as a key building block in the production of critical bile acid derivatives and other advanced therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids.
• Research & Development: Used as a reference standard and starting material in metabolic pathway studies and steroid chemistry research.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for constructing complex steroidal frameworks with specific functional groups.
• Biochemical Studies: Employed in investigations of liver function, cholesterol metabolism, and bile acid receptor activity.

Basic Information

Product Name	3α-Acetyloxy-7-Oxo-5β-Cholan-24-Oic Acid Methyl Ester
CAS No.	10452-65-0
Molecular Formula	C₂₇H₄₂O₆
Molecular Weight	462.62 g/mol
Synonyms	Methyl 3α-Acetoxy-7-oxo-5β-cholan-24-oate; 3α-Acetoxy-7-oxo-5β-cholan-24-oic Acid Methyl Ester; 7-Ketolithocholic Acid 3-Acetate Methyl Ester; Methyl 3α-acetyloxy-7-oxo-5β-cholan-24-oate; 3α-Acetoxy-7-oxolithocholic Acid Methyl Ester; Methyl 3α-acetoxy-7-oxo-5β-cholanate; 7-Oxolithocholic Acid 3-Acetate Methyl Ester
EINECS	Contact for details

Quality Control

Our 3α-Acetyloxy-7-Oxo-5β-Cholan-24-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.